Amidst the ongoing conflict in Gaza, a glimmer of hope emerges as 187,000 children have been vaccinated against polio.** The U.N. World Health Organization aims to reach 640,000 children, with the first polio case reported in 25 years. The limited pauses in fighting, facilitated by Israel, have been described as rare moments of hope in the nearly yearlong war. However, the humanitarian catastrophe created by the war poses challenges for the vaccination campaign. **Despite the challenges, health officials remain hopeful that the campaign will prevent a potential outbreak and protect the children of Gaza.